Manejo odontológico en paciente con síndrome de Cornelia de Lange / Dental treatment of a patient with Cornelia de Lange syndrome

El síndrome de Cornelia de Lange (SCdL) es un trastorno genético poco frecuente y se atribuye principalmente a mutaciones en los genes NIPBL, SMC3 y SMC1A. Sus principales características clínicas son múltiples anomalías congénitas, dimorfismo facial, hirsutismo, hipertricosis, retraso psicomotor, discapacidad intelectual, restricción del crecimiento prenatal y postnatal, anomalías de manos y pies, así como malformaciones congénitas que afectan a distintos órganos. En pacientes con SCdL es necesario hacer hincapié en la higiene oral debido a la discapacidad intelectual que puede presentarse y asegurarse de que se realiza una adecuada valoración y saneamiento dental de forma periódica con el fin de prevenir enfermedades bucodentales. El objetivo de este reporte de caso es describir el manejo odontológico de un paciente de 10 años con SCdL y revisar las características clínicas y hallazgos radiológicos presentes en la cavidad oral (AU)

Cornelia de Lange syndrome (CdLS) is a rare genetic disorder and is principally attributed to mutations in the NIPBL, SMC3 and SMC1A genes. The main clinical characteristics are multiple congenital anomalies, facial dimorphism, hirsutism, hypertrichosis, psychomotor retardation, intellectual disability, prenatal and postnatal growth restriction, hand and foot anomalies, as well as congenital malformations affecting different organs. In patients with CDLS, it is necessary to focus on oral hygiene due to the intellectual disability that may be present and to ensure that adequate dental valuation and hygiene is routinely performed in order to prevent oral diseases. The aim of this case report is to describe the dental management of a 10-year-old patient with CDLS and review the clinical characteristics and radiological findings that are present in the oral cavity (AU)

Coincidencia de criterios para el manejo quirúrgico de caninos impactados/retenidos entre ortodoncistas y cirujanos maxilofaciales: estudio piloto / Criteria agreement for the surgical management of impacted/retained canines among orthodontists and maxillofacial surgeons: a pilot study

Introducción: Los caninos son piezas dentarias consideradas como importantes en el sistema estomatognático. En la actualidad existe una gran cantidad de pacientes con caninos impactados en México y el tratamiento es desafiante desde una perspectiva diagnóstica y terapéutica para los especialistas. El tratamiento ortodóntico-quirúrgico se ha vuelto el método preferido por los clínicos tanto especialistas en ortodoncia como cirujanos maxilofaciales.Objetivo: Determinar el grado de coincidencia en los criterios para el manejo quirúrgico de caninos impactados/ retenidos.Material y métodos: Fue un estudio observacional descriptivo y analítico. Se aplicó un cuestionario que consistió de 29 preguntas con un tamaño de muestra de 30 ortodoncistas y 30 cirujanos maxilofaciales.Resultados: Este estudio encontró en promedio un nivel moderado de concordancia (54 %) en el manejo de los caninos retenidos entre cirujanos maxilofaciales y ortodoncistas.Conclusiones: Nuestros resultados indican que, aunque existe alguna alineación en las prácticas de manejo entre estos dos grupos profesionales, también hay una considerable variabilidad. Esto puede reflejar diferencias en la formación, experiencia y preferencias individuales. A pesar de la limitación de una muestra pequeña, estos hallazgos sugieren la necesidad de directrices clínicas más claras y/o formación adicional para mejorar la coherencia en el manejo de los caninos retenidos. (AU)

Introduction: Canines are dental pieces considered as important in the stomatognathic system. Currently, there is a large number of patients with impacted canines in Mexico, and treatment is challenging from a diagnostic and therapeutic perspective for specialists. Orthodonticsurgical treatment has become the preferred method by clinicians, both orthodontics specialists and maxillofacial surgeons.Objective: To determine the degree of agreement in the criteria for the surgical management of impacted/retained canines.Materials and methods: It was a descriptive and analytical observational study. A questionnaire consisting of 29 questions was applied with a sample size of 30 orthodontists and 30 maxillofacial surgeons.Results: This study found on average a moderate level of agreement (54 %) in the management of retained canines between maxillofacial surgeons and orthodontists.Conclusions: Our results indicate that, although there is some alignment in management practices between these two professional groups, there is also considerable variability. This may reflect differences in training, experience, and individual preferences. Despite the limitation of a small sample, these findings suggest the need for clearer clinical guidelines and/or additional training to improve consistency in the management of retained canines. (AU)

Correlación de los días de estancia hospitalaria con el índice neutrófilo-linfocítico en pacientes con diagnóstico de angina de Ludwig / Correlation of the days of hospital stay with the neutrophillymphocyte ratio in patients with a diagnosis of Ludwig's angina: pilot study

Introducción: El objetivo del presente estudio es correlacionar los días de estancia hospitalaria con el índice neutrófilo-linfocitico (INL) como biomarcador, en los pacientes con diagnóstico de angina de Ludwig que fueron admitidos en urgencias. Pacientes y métodos: Se realizó una búsqueda en los expedientes clínicos del hospital, donde solo se obtuvieron los que tenían diagnóstico de angina de Ludwig desde junio de 2016 hasta junio de 2020, y que cumplieran con los criterios de selección. Posteriormente se recabaron los datos sociodemográficos, días de hospitalización, biometría hemática y valores de neutrófilos y linfocitos para su posterior análisis estadístico. Resultados: Obtuvimos 21 pacientes (9 mujeres y 12 hombres). La edad promedio fue de 43,1 años (rango: 27-70 años). Se transformó la variable de días de hospitalización: en corta estancia hospitalaria aquellos pacientes que estuvieron hospitalizados 5 días o menos; y los de larga estancia hospitalaria aquellos pacientes que estuvieron hospitalizados 6 días o más, para el INL se consideró un índice alto aquellos pacientes que se encontraran con un INL ≥ 6 y un índice bajo aquellos pacientes con un índice ≤ 5, tomando en cuenta el punto de corte con respecto a estudios previamente realizados. Se observó que aquellos pacientes con un INL alto tuvieron una estancia hospitalaria larga, y de acuerdo con los resultados obtuvimos significación estadística (p = 0,02). Conclusiones: El INL parece ser un buen biomarcador para predecir los días de estancia hospitalaria de los pacientes con angina de Ludwig. Sin embargo, se necesitan más estudios para confirmar nuestros resultados. (AU)

Introduction: The aim of this study is to correlate the number of days of hospital stay with the neutrophil-lymphocyte index (NLI) as a biomarker in patients diagnosed with Ludwig's angina who were admitted to the emergency department. Patients and methods: A search was conducted in the hospital's medical records, where only those with a diagnosis of Ludwig's angina from June 2016 to June 2020 and that met the selection criteria were obtained. Afterwards, sociodemographic data, days of hospitalization, hematological parameters, and values of neutrophils and lymphocytes were collected for subsequent statistical analysis. Results: We obtained 21 patients (9 females and 12 males). The average age was 43.1 years (range: 27-70 years). The variable of days of hospitalization was transformed into: short hospital stay for patients who were hospitalized for 5 days or less, and long hospital stay for patients who were hospitalized for 6 days or more. For the NLI, a high index was considered for patients with an NLI ≥ 6 and a low index for patients with an NLI ≤ 5, taking into account the cut-off point with respect to previously conducted studies. We observed that patients with a high NLI had a long hospital stay and according to the results, we obtained statistical significance (p = 0.02). Conclusions: The NLI appears to be a good biomarker for predicting the number of days of hospital stay for patients with Ludwig's angina. However, more studies are needed to confirm our results. (AU)

Saliva: What Dental Practitioners Should Know about the Role of This Biofluid in the Transmission and Diagnostic of SARS-CoV-2.

A novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak has become a global ongoing pandemic. This pandemic represents a great work risk for all health professionals, it includes dental professionals who are in constant contact with saliva, which represents one of the main routes of transmission of the disease. This is due to the fact that a wide variety of oral tissues and cells are susceptible to infection by SARS-CoV-2 and that they express the ACE2 receptor, which is the main route of entry of the virus into cells, as well as the proteins TMPRSS and furin that contributes to the binding of the virus to the host cells. According to recent studies, some of the oral cells most susceptible to infection by SARS-CoV-2 are the epithelial cells of the salivary glands. This explains the presence of the virus in the saliva of infected patients and provides scientific evidence that supports the use of saliva as a biofluid that offers the opportunity to develop new detection and diagnostic techniques. This is because saliva is much easier to collect compared to nasopharyngeal swab. However, the presence of the virus in saliva, also represents a great source of transmission, since the main form of infection is through microscopic drops that are generated when infected people cough or sneeze. Likewise, health professionals, such as dentists are exposed to contagion through saliva. The objective of this review article is to provide a perspective on the main cells and tissues that can be affected by the virus, the risk of contagion that the presence of the virus in saliva represents for dentists; and the new techniques developed from saliva samples for the diagnosis and surveillance of SARS-CoV-2 infection. This review is expected to contribute to the knowledge of oral health professionals about the risk of saliva in the spread of SARS-CoV-2, but also its advantages as a diagnostic tool for pandemic control. In conclusion, the authors can mention that information that provides more scientific evidence of the mechanisms of infection of the coronavirus in oral cells and tissues is being published continually. This also explains the presence of the virus in the saliva of infected people and the risk of contagion that this means. It also provides scientific evidence of the use of saliva as a biofluid for the detection, diagnosis, monitoring, and control of the spread of the virus.

Pain and Anxiety Levels Using Conventional versus Computer-Controlled Local Anesthetic Systems in Pediatric Patients: A Meta-Analysis.

The objective of this systematic review and meta-analysis was to compare the pain/anxiety levels associated with the anesthetic process by conventional and computer-controlled delivery systems (CCDS) in children. Four electronic databases (PubMed, EMBASE, Scopus, Google Scholar, and Dentistry & Oral Science Source/EBSCO) were comprehensively explored for eligible studies, in English or Spanish, published from January 1995 to December 2019. A systematic literature review and meta-analysis were conducted according to the PRISMA statement, including only randomized controlled clinical trials. An exhaustive search was performed in different electronic databases under a specific PICO-posed question. Relevant studies were selected based on titles and abstracts, and the full texts were retrieved. From these articles, important information was extracted. Wand demonstrated significantly lower pain than the conventional injection did. In the subgroup by pain scale analysis, the Facial Image Scale and Wong-Baker Faces Pain Scale showed a significant difference in favor of the CCDS. In general, the reviewed evidence shows that less perceived pain and anxiety occur when the local anesthetic technique is performed with a CCDS than with the traditional technique.

Dental pain and associated factors in Mexican adolescents and young adults: a cross-sectional study.

OBJECTIVE: To identify the factors associated with the prevalence of dental pain in Mexican adolescents and young adults. MATERIAL AND METHODS: This is a cross-sectional study in which data from 638 Mexican subjects, 16-25 years of age, who were randomly selected from college applicants, were analysed. Questionnaires were administered to collect sociodemographic, economic and behavioural variables. Clinical examinations were carried out to determine the decayed, missing and filled teeth (DMFT) index. The outcome variable was dichotomised as 0 (no dental pain in the last 12 months) or 1 (dental pain in the last 12 months). Statistical analyses included binary logistic regression. RESULTS: Average age was 18.76 ± 1.76 years, and 49.2% of participants were women. Prevalence of dental pain was 34.0%. In the final model, variables significantly (P < 0.05) associated with the experience of dental pain were the use of preventive dental services (OR = 0.34), being a former smoker (OR = 2.37), self-report of very poor/poor oral health (OR = 1.94) or fair oral health (OR = 1.94), self-reported dental disease (OR = 2.06) or gingival disease (OR = 2.84). CONCLUSIONS: The prevalence of dental pain was associated with self-reported oral health status, preventive dental visits and smoking; these results have implications for dental practice. We found that recent experience of dental pain was common in young adults, being reported by one out of three subjects.

Evaluación radiográfica de la presencia/agenesia de terceros molares en una población infantil Mexicana / Radiographic Evaluation of the Presence/Agenesis of Third Molars in a Mexican Child Population

RESUMEN En el ser humano, el tercer molar es el órgano dentario que más variaciones presenta durante su desarrollo embriológico, y es causa de diversas alteraciones y malestares durante su proceso de erupción. Se ha señalado que la agenesia del tercer molar tiene una prevalencia entre 9 y 37%. El objetivo del presente estudio transversal comparativo fue evaluar radiográficamente la presencia/ausencia de gérmenes de terceros molares (G3M) en pacientes pediátricos de origen mexicano. Se analizaron 513 radiografías panorámicas de pacientes que asistieron al Posgrado en Estomatología Pediátrica de la Universidad Autónoma de San Luis Potosí (México), durante los años 2011 a 2017. Se tomaron como criterios de inclusión, pacientes entre los 7 y 18 años de edad, sexo indistinto; se excluyeron pacientes con antecedentes de extracción de alguno de los terceros molares, tratamiento ortodóntico previo, enfermedades congénitas y/o síndromes asociados. Se compararon las frecuencias y prevalencias de agenesia de terceros molares, en total y por cuadrantes, comparando por sexo y grupo de edad. 245 radiografías panorámicas correspondieron al sexo femenino y 268 al masculino. La prevalencia total de agenesia del G3M fue estimada en casi 56%, y el grupo de edad de 7-8 años mostró el mayor porcentaje; sin embargo, cuando este grupo de edad se excluyó del análisis, dicha prevalencia disminuyó a 27.3%. Los cuadrantes mandibulares mostraron mayor porcentaje de agenesia. No hubo diferencia estadística significativa en la comparación por sexo. La prevalencia total de agenesia del G3M reportada en el presente estudio se encuentra muy por encima de los parámetros internacionales. Es muy posible que la falta de visualización radiográfica de agenesia de los terceros molares haya sido errónea en algunos casos debido a la ausencia frecuente de indicios de calcificación de este diente durante las edades tempranas (7-8 años). El análisis ajustado proporcionó un valor de prevalencia más acorde con los estándares reconocidos por la literatura dental.

ABSTRACT In the human being, third molar is the tooth that exhibits more variants during its embryologic development, usually causing diverse anomalies and discomfort when erupting to the oral cavity. It has been pointed out that the prevalence of third molar agenesis is between 9 to 37%. The aim of the present comparative cross- sectional study was to radiographically assess the presence/absence of third molar germs (G3M) in a sample of pediatric patients of Mexican origin. A total of 513 panoramic radiographs were analyzed from patients attending the Pediatric Dentistry Postgraduate Program ( San Luis Potosí University, México), during the years 2011 to 2017. Inclusion criteria were patients between 7 and 18 years old, any gender; children with antecedents of a third molar extraction, previous orthodontic treatment, or with an associated congenital or systemic condition were excluded. Total prevalence G3M agenesis was calculated. Then, statistical comparisons of agenesia proportions per dental quadrant, gender, and age group were performed. 245 panoramic radiographs corresponded to the female gender, while 268 belonged to the male gender. The total prevalence of G3M agenesia was estimated in nearly 56%, and the 7-8 years old group exhibited the highest proportion; however, when this age group was excluded from the analysis, such prevalence decreased to 27.3%. Both mandibular quadrants showed higher proportions of G3M agenesia. There were no significant differences between genders. The total prevalence reported in the present study was found to be well above regarding the international parameters. It is quite possible that lack of radiographic visualization of G3M had been inaccurate in some cases due to the common absence of calcification traces from those teeth during early ages (7-8 years old). The adjusted analysis provided a prevalence value more in line with the recognized standards in the dental literature.

Agreement analysis of three mandibular third molar retention classifications.

INTRODUCTION: Pell & Gregory and Winter classifications are basic in third molar categorization; Sánchez-Torres classification is used in Mexico, but it has not been previously evaluated. OBJECTIVE: To assess the degree of agreement in the radiographic evaluation of impacted mandibular third molar with the use of three classifications: Pell & Gregory, Winter and Sánchez-Torres. METHOD: Observational, descriptive, inter-observer degree of agreement study that included 10 oral and maxillofacial surgeons and 10 training residents, who recorded the radiographic categorization of third mandibular molars (left and right) according to Pell and Gregory, Sánchez-Torres and Winter classifications. Inter-observer degree of agreement was assessed with Fleiss' kappa test. RESULTS: Pell and Gregory classification obtained the lowest degree of agreement (kappa = 0.05 and 0.185), followed by Sánchez-Torres classification (kappa = 0.125 and 0.326); Winter had the best agreement, with kappa = 0.28 and 0.636 for oral and maxillofacial surgeons and training residents, respectively. CONCLUSION: The Winter classification showed an acceptable (moderate) degree of agreement to classify mandibular third molars by training residents.

INTRODUCCIÓN: Las clasificaciones de Pell y Gregory y de Winter son básicas en la categorización de terceros molares; la clasificación de Sánchez Torres es usada en México, pero no había sido evaluada previamente. OBJETIVO: Evaluar el grado de acuerdo en la valoración radiográfica de terceros molares mandibulares impactados, con el empleo de tres clasificaciones: Pell y Gregory, Winter y Sánchez Torres. MÉTODO: Estudio observacional, descriptivo, de concordancia interobservador, que incluyó a 10 cirujanos orales y maxilofaciales y 10 residentes en formación, quienes registraron la categorización radiográfica de terceros molares mandibulares (izquierdos y derechos) de acuerdo con las clasificaciones de Pell y Gregory, Sánchez Torres y Winter. Se evaluó el grado de acuerdo entre observadores mediante la prueba de kappa de Fleiss. RESULTADOS: La clasificación de Pell y Gregory obtuvo el menor grado de acuerdo (kappa = 0.05 y 0.185), seguida de la clasificación de Sánchez Torres (kappa = 0.125 y 0.326); el mejor valor lo obtuvo la clasificación de Winter, con kappa = 0.28 y 0.636 para cirujanos orales y maxilofaciales y residentes en formación, respectivamente. CONCLUSIÓN: La clasificación de Winter mostró un grado de acuerdo aceptable (moderado) para categorizar terceros molares mandibulares en los residentes en formación.

Análisis de concordancia de tres clasificaciones de terceros molares mandibulares retenidos / Agreement analysis of three mandibular third molar retention classifications

Resumen Introducción: Las clasificaciones de Pell y Gregory y de Winter son básicas en la categorización de terceros molares; la clasificación de Sánchez Torres es usada en México, pero no había sido evaluada previamente. Objetivo: Evaluar el grado de acuerdo en la valoración radiográfica de terceros molares mandibulares impactados, con el empleo de tres clasificaciones: Pell y Gregory, Winter y Sánchez Torres. Método: Estudio observacional, descriptivo, de concordancia interobservador, que incluyó a 10 cirujanos orales y maxilofaciales y 10 residentes en formación, quienes registraron la categorización radiográfica de terceros molares mandibulares (izquierdos y derechos) de acuerdo con las clasificaciones de Pell y Gregory, Sánchez Torres y Winter. Se evaluó el grado de acuerdo entre observadores mediante la prueba de kappa de Fleiss. Resultados: La clasificación de Pell y Gregory obtuvo el menor grado de acuerdo (kappa = 0.05 y 0.185), seguida de la clasificación de Sánchez Torres (kappa = 0.125 y 0.326); el mejor valor lo obtuvo la clasificación de Winter, con kappa = 0.28 y 0.636 para cirujanos orales y maxilofaciales y residentes en formación, respectivamente. Conclusión: La clasificación de Winter mostró un grado de acuerdo aceptable (moderado) para categorizar terceros molares mandibulares en los residentes en formación.

Abstract Introduction: Pell & Gregory and Winter classifications are basic in third molar categorization; Sánchez-Torres classification is used in Mexico, but it has not been previously evaluated. Objective: To assess the degree of agreement in the radiographic evaluation of impacted mandibular third molar with the use of three classifications: Pell & Gregory, Winter and Sánchez-Torres. Method: Observational, descriptive, inter-observer degree of agreement study that included 10 oral and maxillofacial surgeons and 10 training residents, who recorded the radiographic categorization of third mandibular molars (left and right) according to Pell and Gregory, Sánchez-Torres and Winter classifications. Inter-observer degree of agreement was assessed with Fleiss' kappa test. Results: Pell and Gregory classification obtained the lowest degree of agreement (kappa = 0.05 and 0.185), followed by Sánchez-Torres classification (kappa = 0.125 and 0.326); Winter had the best agreement, with kappa = 0.28 and 0.636 for oral and maxillofacial surgeons and training residents, respectively. Conclusion: The Winter classification showed an acceptable (moderate) degree of agreement to classify mandibular third molars by training residents.

Dentinogenesis Imperfecta Type II in Children: A Scoping Review.

Dentinogenesis Imperfecta type II (DI2), also known as hereditary opalescent dentin, is one of the most common genetic disorders affecting the structure of dentin, not related with osteogenesis imperfecta, which involves both primary and permanent dentitions. The purpose of this article is to perform a scoping review of the published peer-reviewed literature (1986-2017) on DI2 management in children and to outline the most relevant clinical findings extracted from this review. Forty four articles were included in the present scoping review. According to the extracted data, the following are the most important tasks to be performed in clinical pediatric dentistry: to re-establish the oral mastication, esthetics, and speech, and the development of vertical growth of alveolar bone and facial muscles; to reduce the tendency to develop caries, periapical lesions and pain; to preserve vitality, form, and size of the dentition; to avoid interfering with the eruption process of permanent teeth; to decrease the risk of tooth fractures and occlusion disturbances; to return the facial profile to a more normal appearance; and to prevent or treat possible temporomandibular joint problems. Therefore, Pediatric Dentists should bear in mind that early diagnosis and treatment, together a long-term follow-up of DI2 in children, continue to be the best approaches for achieving enhanced patient psychological well-being and, in consequence, their quality of life.

El expediente clínico electrónico: una opción con posibilidades ilimitadas / The electronic clinical file: an option with unlimited possibilities

El expediente clínico se define como el conjunto de datos médicos y clínicos ordenados y detallados en forma cronológica, que permiten al profesional de la salud plantear un diagnóstico sindrómico y nosológico, con su posterior pronóstico, para finalmente llevar un registro del desarrollo de un tratamiento. Refleja la capacidad resolutiva de la clínica o consultorio, así como la capacidad profesional de su personal, de ahí la importancia de tener un expediente clínico bien integrado, ordenado, completo, legible y en apego a la normatividad vigente (AU)

The clinical file is defined as a set of medical and clinical data, which are ordered and chronologically detailed, allows the health professional to identify a syndromic and nosological diagnosis, with a later prognosis, to finally make a treatment plan. It reflects the resolutive capacity and the professional capacity of the clinician and his staff. Therefore, it becomes a legal document of the greatest importance, having to have the characteristics of being well integrated, orderly, complete, legible and in compliance with current regulations (AU)

Prevalencia de Bruxismo y Trastornos Temporomandibulares Asociados en una Población de Escolares de San Luis Potosí, México / Prevalence of Bruxism and Associated Temporomandibular Disorders in a Population of School Children of San Luis Potosí, México

RESUMEN: El término "Transtornos Temporomandibulares" (TTM) incluye numerosos problemas clínicos asociados con las articulaciones temporomandibulares, músculos de la masticación y otras estructuras asociadas. El bruxismo, un hábito oral parafuncional, consiste en rechinar o apretar de manera rítmica e involuntaria los dientes, lo que puede conducir a trauma oclusal y problemas articulares. El objetivo del estudio fue determinar la frecuencia y prevalencia de signos y síntomas de TTM y bruxismo en niños escolares de 6 a 12 años, en una población de San Luis Potosí, México. Se empleó un diseño transversal descriptivo en una muestra de 314 participantes, estudiantes de una escuela primaria de la ciudad de San Luis Potosí, México. Los participantes fueron seleccionados aleatoriamente en forma estratificada y polietápica. La muestra total consistió en 153 femeninos y 161 masculinos. Los signos y síntomas de TTM más frecuentes fueron la alteración de la función de la ATM (35 %), seguido por los ruidos y chasquido articulares (29,2 %). En los sujetos con diagnóstico de bruxismo, la alteración más frecuente fueron molestias asociadas en la ATM (19,4 %), dolor de cabeza (17,8 %) y atrición dental (16,5 %).

ABSTRACT: The term "Temporomandibular disorders" (TTM) includes numerous clinical problems associated with joint temporomandibular, muscles of mastication and other associated structures. Bruxism, oral parafunctional habit, consists of grinding or clenching of involuntary, rhythmic manner, which can lead to trauma, occlusal and problems joint. The objective of the study was to determine the frequency and prevalence of signs and symptoms of DTM and bruxism in school children aged 6 to 12, in a population of San Luis Potosí, México. A crosssectional descriptive design was used in a sample of 314 participants, students of a primary school in the city of San Luis Potosi, Mexico. The participants were randomly selected in tiered form and conglomerated. The total sample consisted of 153 female and male 161. The signs and symptoms of TMD frequent were alteration of the function of the ATM (35 %), followed by noise and snap joint (29.2 %). In subjects with a diagnosis of bruxism, the most frequent alteration was associated with TMJ discomfort (19.4 %), headache (17.8 %) and dental attrition (16.5 %).

Non-syndromic craniosynostosis in children: Scoping review

BACKGROUND: Craniosynostosis (CS) is a complex condition consisting of the early fusion of one or more cranial sutures in the intrauterine stage. The affected infant exhibits abnormal head shape at time of birth or shortly thereafter. It can be observed in normal individuals (non-syndromic CS or NSCS) or as a part of a multisystem syndrome. The purposes of the present article were to carry out a scoping review on Non-Syndromic CS and to discuss the most important findings retrieved. MATERIAL AND METHODS: The steps of this scoping review were as follows: first, to pose a research question; second, to identify relevant studies to answer the research question; third, to select and retrieve the studies; fourth, to chart the critical data, and finally, to collate, summarize, and report the results from the most important articles. Relevant articles published over a 20-year period were identified and retrieved from five Internet databases: PubMed; EMBASE; Cochrane Library; Google Scholar, and EBSCO. RESULTS: Fourteen articles were finally included in the present scoping review. The following four most important clinical issues are discussed: (I) normal cranial development, clinical manifestations, and pathogenesis of NCSC; (II) clinical evaluation of NCSC; (III) treatment and post-surgical follow-up; and (IV) additional considerations. CONCLUSIONS: NSCS may be present with associated head shapes. Multiple early surgical reconstructive options are currently available for the disorder. Pediatric Dentistry practitioners must be familiarized with this condition and form part of a multi-approach health team as those responsible for the opportune oral health care of the affected child

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Clinical and Radiographic Characteristics as Predictive Factors of Swelling and Trismus after Mandibular Third Molar Surgery: A Longitudinal Approach.

Introduction: Factors that contribute to swelling and trismus are complex, and they are originated by surgical trauma. The aim of the present study was to determine whether clinical and radiographic factors could predict the level of swelling and trismus after lower third molar surgery, through longitudinal approach. Methodology: A prospective longitudinal trial was carried out. Forty-five patients of both genders with clinical and radiographic diagnosis of asymptomatic mandibular impacted third molar and with no intake of analgesic or anti-inflammatory drugs 12 h prior to surgery were recruited and evaluated in a 72 h follow-up period. A mixed repeated measures model and backward and restricted maximal likelihood methods were used to analyze the data. Results: Male gender, body mass index (BMI), the relation to the lingual and buccal walls, and age were determinants for predicting postoperative swelling and for exerting a significant influence (P < 0.05). Conclusions: This study suggests the association of male gender, the relation to lingual and buccal walls, BMI, and age with measurement of swelling.

Evaluación del efecto sedativo del Midazolam con y sin Ketamina, por vía subcutánea, en pacientes dentales pediátricos / Evaluation of the Sedative Effect of Midazolam with and Without Ketamine, by Subcutaneous Via in Pediatric Dental Patients

Resumen El miedo y la ansiedad de los niños por el tratamiento dental pueden conducir a dificultades en el manejo de la conducta por parte del profesional, lo cual puede ser una barrera para el éxito del tratamiento dental. Los niños no cooperadores pueden necesitar recibir tratamiento dental bajo sedación, la que se indica cuando la guía de comportamiento no farmacológico no tiene éxito. Existen ensayos controlados aleatorios que comparan diferentes protocolos sedantes para procedimientos dentales; sin embargo, la evidencia de superioridad de una forma sobre otra es débil. El objetivo del presente estudio es evaluar el efecto sedativo de Midazolam por vía subcutánea, con y sin ketamina, en procedimientos odontológicos realizados en pacientes pediátricos no cooperadores. Se llevó a cabo un ensayo clínico aleatorizado, cruzado, con cegamiento simple, en 13 niños (10 del género masculino y 3 del femenino) de 19 a 48 meses de edad, ASA I y comportamiento Frankl I. Los dos métodos se aplicaron en el mismo paciente, y el orden de los mismos fue asignado aleatoriamente, para las dos citas de tratamiento. En cada sesión se evaluaron: el comportamiento general del paciente, los movimientos corporales y el llanto, por medio de la escala de Houpt modificada. Además, se monitorearon la frecuencia cardíaca y la saturación de oxígeno por medio de un oxímetro de pulso.

Abstract Children's fear and anxiety about dental treatment can lead to difficulties in the behavior management by the practitioner, which can be a barrier to successful dental treatment. Non cooperative children may need dental treatment under sedation, which is indicated when the non-pharmacological behavioral guidance is unsuccessful. There are randomized controlled trials comparing different sedative protocols for dental procedures; however, evidence of superiority from one form over another is weak. The aim of the present study was to evaluate the sedative effect of midazolam subcutaneously, with and without ketamine, on dental procedures performed in non-cooperative pediatric patients. A randomized, crossover clinical trial with single blinding was performed in 13 children (10 males and 3 females) from 19 to 48 months of age, ASA I and Frankl I behavior. The two methods were applied in the same patient, and the order of the same was assigned randomly, for the two treatment appointments. In each session were evaluated the patient's general behavior, body movements and crying through the modified Houpt scale. In addition, heart rate and oxygen saturation were monitored by means of a pulse oximeter.

Prophylactic Extraction of Third Molars: Evidence-Based Dentistry

his new perspective article was performed to investigate the evidence from published dental literature about the prophylactic extraction of asymptomatic (or disease-free) impacted third molars (ITM) in adolescents and young adults. This clinical procedure is common until today and has been the origin of controversy among the dental community worldwide. However, evidence-based data from wellconducted clinical studies and systematic reviews are not sufficient to justify the routine prophylactic extraction of ITM. Active surveillance at regular intervals has been proposed as a better management strategy. As a conclusion, surgical removal of ITM is only justified in the presence of specific pathosis, independently of the patient's age.

l presente artículo se realizó para investigar la evidencia en literatura dental publicada sobre la extracción profiláctica de terceros molares impactados asintomáticos (o libres de enfermedad) (TMI) en adolescentes y adultos jóvenes. Este procedimiento clínico es común y ha sido el origen de la controversia entre la comunidad dental en todo el mundo. Sin embargo, los datos basados en evidencia de estudios clínicos y revisiones sistemáticas no son suficientes para justificar la extracción profiláctica rutinaria de TMI. La vigilancia activa a intervalos regulares se ha propuesto como una mejor estrategia de manejo. Como conclusión, la remoción quirúrgica de TMI sólo se justifica en presencia de patología específica, independientemente de la edad del paciente.

Eficacia del uso del plasma rico en factores de crecimiento en defectos periodontales distales de segundos molares inferiores, posterior a la extracción de un tercer molar mandibular / Efficacy of using plasma rich in growth factors in periodontal defects in lower distal second molar after extracting a mandibular third molar

Objetivo. El propósito de este estudio fue evaluar la eficacia de la aplicación de plasma rico en factores de crecimiento (PRFC), dentro de un defecto periodontal distal, a los segundos molares inferiores después de la extracción de un tercer molar mandibular. Material y métodos. Se realizó un ensayo clínico controlado, doble ciego, aleatorizado en 20 pacientes sanos, con defectos óseos bilaterales posterior a la extracción de un tercer molar retenido. Los pacientes fueron dividos en grupo experimental y control. Se realizaron mediciones de nivel clínico de inserción en el área distal del segundo molar previamente a la cirugía, usando una férula de acetato, con el fin de tener la misma referencia de medición posterior al procedimiento. Las mediciones posquirúrgicas fueron realizadas a las semanas 1, 4 y 12. Estas mediciones, así como los tiempos de evaluación, fueron analizados por medio de las pruebas de t de Student, Chi2 y Kruskal-Wallis. Resultados. Las variables demostraron similitud en cuanto a edad, sexo, dificultad y duración de los tiempos quirúrgicos. La medición del nivel clínico de inserción preoperatoria en milímetros fue de 2,68±0,56 vs. 2,63±0,50 (experimental vs. control). Durante la primera semana posterior al procedimiento los resultados fueron: 5,37±1,81 vs. 5,35±1,72; y a los 3 meses la recuperación fue similar en ambos grupos casi a sus niveles basales (2,43±0,89 vs. 2,55±0,92). Conclusiones. No se encontró diferencia significativa con el uso de PRFC en cuanto a ganancia en el nivel clínico de inserción periodontal en el área distal de segundos molares después de la extracción de terceros molares inferiores retenidos (AU)

Purpose. The aim of this study was to evaluate the effectiveness of the application of plasma rich in growth factors (CFRP) in a distal periodontal defect of the lower second molars after extraction of a third molar. Material and methods. A randomised, controlled, and double-blind clinical trial, was conducted on 20 healthy patients with bilateral defects after the extraction of an impacted third molar. The patients were divided into experimental and control groups. Measurements of clinical attachment level were performed in the distal area of the second molar prior to surgery using an acetate splint in order to have the same reference measurement after the procedure. Post-surgical measurements were performed at 1, 4, and 12 weeks. These measurements, as well as evaluation times, were analysed using the Student t-Test, χ2 and Kruskal-Wallis Test. Results. The variables showed similarity in age, gender, difficulty, and length of the surgical times. The measurements prior to clinical insertion were 2.68±0.56 vs. 2.63±0.50 (experimental vs. control). During the first week after the procedure, the results were: 5.37±1.81 vs. 5.35±1.72; and at 3 months the recovery almost to baseline was similar in both groups (2.43±0.89 vs. 2.55±0.92). Conclusions. No significant difference was found with the use of CFRP as regards achieving attachment at clinical level in the distal area of second molars after extraction of third molars (AU)

Dental Management of a Child with Incidentally Detected Hemophilia: Report of a Clinical Case.

Children with hemophilia (A or B) are at risk for bleeding episodes, which rank from mild mucosal/soft tissues bleeding to life-threatening hemorrhages. This report describes the dental/medical management provided to an 8.10-year-old patient suffering from uncontrolled bleeding after a surgical procedure to expose both permanent upper central incisors, in which hemophilia was a pure incidental finding. Additionally, diverse precautions to be considered during the dental clinical treatment of hemophilic children are discussed.

Comparison of the analgesic efficacy of oral ketorolac versus intramuscular tramadol after third molar surgery: A parallel, double-blind, randomized, placebo-controlled clinical trial

BACKGROUND: Preemptive analgesia is considered an alternative for treating the postsurgical pain of third molar removal. The aim of this study was to evaluate the preemptive analgesic efficacy of oral ketorolac versus intramuscular tramadol after a mandibular third molar surgery. MATERIAL AND METHODS: A parallel, double-blind, randomized, placebo-controlled clinical trial was carried out. Thirty patients were randomized into two treatment groups using a series of random numbers: Group A, oral ketorolac 10 mg plus intramuscular placebo (1 mL saline solution); or Group B, oral placebo (similar tablet to oral ketorolac) plus intramuscular tramadol 50 mg diluted in 1 mL saline solution. These treatments were given 30 min before the surgery. We evaluated the time of first analgesic rescue medication, pain intensity, total analgesic consumption and adverse effects. RESULTS: Patients taking oral ketorolac had longer time of analgesic covering and less postoperative pain when compared with patients receiving intramuscular tramadol. CONCLUSIONS: According to the VAS and AUC results, this study suggests that 10 mg of oral ketorolac had superior analgesic effect than 50 mg of tramadol when administered before a mandibular third molar surgery

Comparison of the analgesic efficacy of preoperative/postoperative oral dexketoprofen trometamol in third molar surgery: A randomized clinical trial.

The aim of this study was to compare the efficacy of preoperative and postoperative dexketoprofen trometamol for pain control after third molar surgery. Sixty subjects indicated for impacted mandibular third molar surgery were randomly assigned to two groups: preoperative (group 1, n = 30) and postoperative (group 2, n = 30) administration. Group 1 received 25 mg of dexketoprofen trometamol 30 min before surgery and 1 placebo capsule (same color and size with active drug) immediately after surgery. Group 2 received the placebo capsule 30 min before surgery and 25 mg of dexketoprofen trometamol immediately after surgery. Pain intensity was assessed using a numeric rating scale (NRS) during the first 8 h. The time of the need for a second dose of dexketoprofen trometamol, after the first administration, was recorded. The data were analyzed using mixed-model repeated-measures (MMRM), Wilcoxon rank-sum, and Kaplan-Meier analysis. After the 8 h period, no statistically significant difference was observed in the intensity of pain (MMRM, p = 0.41); and no significant difference in the time for a second dose (p = 0.956). In conclusion, preoperative administration of dexketoprofen trometamol is a reasonable clinical approach that is as effective as conventional postoperative pharmacological treatment, with the advantage of allowing early analgesia before pain develops. (ClinicalTrials.gov: NCT02380001).